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UnknownNCT03795155

Prospective Genomics Initiative on Multiple Synchronous Lung Cancer (PGI-MSLC)

Status
Unknown
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
RenJi Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This prospective study is to characterize the genomic landscape and genetic heterogeneity of multiple synchronous lung cancer (MSLC) in correlation with comprehensive clinical, histopathological and medical imaging information, in order to improve disease diagnosis and tailored treatment for MSLC patients.

Detailed description

* To initiate a prospective registry of MSLC patients with high-quality clinical samples and detailed medical data. * To define the clonal relationship, genomic landscape and potential driver alterations of MSLC using whole-genome sequencing. * To determine the intrapatient and intratumor genetic heterogeneity of MSLC. * To correlate molecular features with clinical parameters and patient outcome. * To serve as a continuous infrastructure for a large variety of research purposes including: A. Diagnostic research B. Prognostic research C. Biological research D. Interventional trial design testing new therapies in MSLC.

Conditions

Timeline

Start date
2018-12-01
Primary completion
2022-11-30
Completion
2023-11-30
First posted
2019-01-07
Last updated
2020-06-11

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03795155. Inclusion in this directory is not an endorsement.

Prospective Genomics Initiative on Multiple Synchronous Lung Cancer (PGI-MSLC) (NCT03795155) · Clinical Trials Directory