Clinical Trials Directory

Trials / Completed

CompletedNCT03795142

A First-time-in-human Study of BGB149

A Phase I Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BGB149 Following Single Dose Administration in Healthy Subjects

Status
Completed
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
24 (actual)
Sponsor
BerGenBio ASA · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

This clinical trial is a Phase I, first-in-human. The study is designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and immunogenicity of BGB149 after single IV doses in healthy male and female subjects. Multiple dose levels will be explored.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBGB149Single Ascending Dose
BIOLOGICALPlaceboMatching placebo

Timeline

Start date
2018-12-19
Primary completion
2019-10-31
Completion
2019-10-31
First posted
2019-01-07
Last updated
2022-03-16

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT03795142. Inclusion in this directory is not an endorsement.

A First-time-in-human Study of BGB149 (NCT03795142) · Clinical Trials Directory