NCT03794141

Genetic Information as a Life Style Change Motivator

Effects of ApoE4 Genotype Information and Intervention Intensity on the Fulfillment of Lifestyle Changes and Sensory Preferences

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 333 (actual)
• Sponsor: Natural Resources Institute Finland · Other Government
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The study investigates whether information on having a risk genotype (ApoE4) and life style advisory information affects lifestyle changes and sensory preferences. The project studies also the ethic aspects of giving the information of risk genotype.

Detailed description

We will run intervention based on our earlier pilot study. It includes intensive intervention and a modification of our earlier pilot intervention. Our intervention methods are general lectures of the effects of healthy diet (Finnish Nutrition Recommendations 2014) and healthy lifestyle for all participants. Effects on motivation, attitudes and preferences will be studied and verified by questionnaires and risk factors of cardiovascular disease and Alzheimer disease by analyzing clinical markers of lipid metabolism, general phenotype markers and profiles of nutritional markers. Nutritional biomarkers will verify also the self-reported changes of diet in the questionnaires and in digital food diaries.

Conditions

• Health Behavior
• Alzheimer Disease, Protection Against

Interventions

Type	Name	Description
BEHAVIORAL	information on the risk gene status	information on risk gene status (APOE4 allele or not) was given before intervention
BEHAVIORAL	life style advise	all test persons were given information on healthy diet and life style

Timeline

• Start date: 2017-01-02
• Primary completion: 2019-03-30
• Completion: 2019-07-31
• First posted: 2019-01-04
• Last updated: 2020-02-26