Clinical Trials Directory

Trials / Terminated

TerminatedNCT03793686

A Study of Safety of PBCLN-003 Following Antibiotic Therapy in Subjects With C.Difficile-associated Diarrhea

A Phase 1 Double Blind, Randomized Clinical Study to Evaluate the Safety of Human Milk Oligosaccharides Following Antibiotic Therapy in Subjects With C. Difficile-associated Diarrhea

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
26 (actual)
Sponsor
Prolacta Bioscience · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This Phase I double blind, randomized clinical study to evaluate the safety of human milk oligosaccharides (HMO) is designed to assess the safety and dosage ranging of PBCLN-003 in adults with Clostridium difficile-associated diarrhea (CDAD). Within 3 dose cohort, subjects will be randomized in a 3:1 ratio to receive PBCLN-003 or placebo.

Conditions

Interventions

TypeNameDescription
DRUGPBCLN-003Investigational drug
DRUGPlaceboPlacebo

Timeline

Start date
2018-12-06
Primary completion
2020-09-01
Completion
2020-09-01
First posted
2019-01-04
Last updated
2020-10-19

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03793686. Inclusion in this directory is not an endorsement.

A Study of Safety of PBCLN-003 Following Antibiotic Therapy in Subjects With C.Difficile-associated Diarrhea (NCT03793686) · Clinical Trials Directory