NCT03793309

Different Doses of Vitamin D and T Regulatory Cells in Preterm Infants

A Randomized Controlled Trial on the Effect of 400 vs. 800 IU of Vitamin D on T Regulatory Cells in Preterm Infants

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 28 Days
• Healthy volunteers: Not accepted

Summary

This study evaluate the effect of two different doses of vitamin D on T-regulatory cells in preterm infants. Half of the subjects receives 400 IU vitamin D and the other half receives 800 IU vitamin D.

Detailed description

Vitamin D, in addition to its bone mineralization effect, is an immune- modulatory agent. Fetal and premature cellular immunity are generally delayed. Whether vitamin D can enhance cellular immunity by increasing T regulatory cells is unknown. The effect of two different doses of vitamin D; 400 IU and 800 IU will be studied.

Conditions

• Prematurity
• Immune Defect

Interventions

Type	Name	Description
DRUG	Vitamin D	Oral vitamin D

Timeline

• Start date: 2017-01-09
• Primary completion: 2017-12-11
• Completion: 2017-12-11
• First posted: 2019-01-04
• Last updated: 2019-01-07