NCT03790254

D Mannose for Prevention and Treatment of RUTIs

Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 500 (actual)
• Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.

Detailed description

A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs. Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.

Conditions

• Recurrent Urinary Tract Infections
• Antibiotic Prophylaxis
• Antibiotic Resistance

Interventions

Type	Name	Description
OTHER	systematic review

Timeline

• Start date: 2010-01-01
• Primary completion: 2018-12-20
• Completion: 2018-12-25
• First posted: 2018-12-31
• Last updated: 2018-12-31

Locations

1 site across 1 country: Italy