NCT03790215

Dydrogesterone in the Treatment of Endometrial Polyps

Prospective One-arm Cohort Study of Dydrogesterone in the Treatment of Endometrial Polyps

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.

Detailed description

Endometrial polyps are a common female endometrial lesion.The long-term unrestrained exposure of estrogen to local tissue is one of the causes of polyp formation.Studies suggested that the progesterone can accelerate the regression rate of endometrial polyps due to its antiestrogenic effects.Based on this, investigators intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.

Conditions

• Endometrial Polyp

Interventions

Type	Name	Description
DRUG	Dydrogesterone	The investigators give participants oral dydrogesterone(as described in arm description).After 3 cycles of treatment, the investigators evaluate the treatment effects.

Timeline

• Start date: 2019-02-01
• Primary completion: 2019-09-30
• Completion: 2019-12-31
• First posted: 2018-12-31
• Last updated: 2020-01-22

Locations

1 site across 1 country: China