NCT03789877

A Home-Based Walking Program and rTMS in Helping Breast Cancer Survivors Get More Physical Activity

Enhancing A Home-Based Walking Intervention Among Breast Cancer Survivors With rTMS: Feasibility and Limited Efficacy Testing

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Roswell Park Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

This trial studies how well a home-based walking program, with or without repetitive transcranial magnetic stimulation, works in helping breast cancer survivors get more physical activity. Physical activity has been shown to improve health outcomes and quality of life among breast cancer survivors and can help lessen certain side effects of treatment such as fatigue, depression, and treatment-related weight gain. Repetitive transcranial magnetic stimulation is a procedure that uses electromagnets to stimulate brain activity. Using rTMS with a home-based walking program may help breast cancer survivors get more physical activity.

Detailed description

PRIMARY OBJECTIVES: I. To examine the effects of 20 hertz (Hz) repetitive transcranial magnetic stimulation (rTMS) on delay discounting rates and multiple measures of self-regulation and walking. OUTLINE: Patients are randomized to 1 of 2 groups. GROUP I: Patients participate in a home-based exercise program of at least 10,000 steps per day (about 30 minutes of daily exercise) for 5 days weekly (150 minutes per week) for 12 weeks. Patients also undergo repetitive transcranial magnetic stimulation over 1 hour for 8 sessions during the first 2 weeks of the walking program. GROUP II: Patients participate in a home-based exercise program of at least 10,000 steps per day (about 30 minutes of daily exercise) for 5 days weekly (150 minutes per week) for 12 weeks. Patients also undergo sham repetitive transcranial magnetic stimulation over 1 hour for 8 sessions during the first 2 weeks of the walking program.

Conditions

• Cancer Survivor
• Invasive Breast Carcinoma

Interventions

Type	Name	Description
OTHER	Physical Activity	Participate in home-based walking program
OTHER	Questionnaire Administration	Ancillary studies
PROCEDURE	Repetitive Transcranial Magnetic Stimulation	Undergo rTMS
PROCEDURE	Sham Intervention	Undergo sham rTMS

Timeline

• Start date: 2019-01-16
• Primary completion: 2021-02-05
• Completion: 2021-02-05
• First posted: 2018-12-31
• Last updated: 2021-10-26

Locations

1 site across 1 country: United States