NCT03789708

Effects of Gum Arabic Supplementation in Hemodialysis Patients

Study of Some Pharmacological and Biochemical Effects of Gum Arabic Supplementation to Hemodilaysis Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: University of Khartoum · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties. Through its effect on intestinal bacteria, it's expected to reduce systemic levels of toxic bacterial metabolites and reduce inflammatory markers.By increasing fecal bacteria mass it's also expected to reduce blood urea level. These changes are potentially beneficial to hemodialysis patients who suffer from disturbed intestinal flora and a chronic inflammatory status. The investigators hypothesize that supplementing the diet of hemodialysis patients with Gum Arabic for four weeks would reduce inflammatory markers, increase total anti-oxidant capacity and reduce blood urea concentration.

Conditions

• Kidney Failure, Chronic

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Gum Arabic	Instantly soluble granules of Gum Arabic; 100% Acacia Senegal
OTHER	Placebo	Maltodextrin powder, easily soluble

Timeline

• Start date: 2018-11-01
• Primary completion: 2019-03-01
• Completion: 2019-06-01
• First posted: 2018-12-31
• Last updated: 2019-01-03

Locations

1 site across 1 country: Sudan