Clinical Trials Directory

Trials / Completed

CompletedNCT03789292

A Study to Compare Efficacy and Safety of CT-P17 With Humira in Patients With Active Rheumatoid Arthritis

A Randomized, Active-Controlled, Double-Blind, Phase 3 Study to Compare Efficacy and Safety of CT-P17 With Humira When Co-administered With Methotrexate in Patients With Moderate to Severe Active Rheumatoid Arthritis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
648 (actual)
Sponsor
Celltrion · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is a Phase III Study to Compare Efficacy and Safety of CT-P17 with Humira in Patients With Active Rheumatoid Arthritis

Detailed description

CT-P17, containing the active ingredient adalimumab, is a recombinant humanized monoclonal antibody that is being developed as a similar biological medicinal product to Humira. The purpose of this study is to demonstrate similar efficacy and safety of CT-P17 and Humira in patients with moderate to severe rheumatoid arthritis when co-administered with methotrexate.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCT-P17 SCSubcutaneous injection of Adalimumab 40mg every two weeks
BIOLOGICALHumira SCSubcutaneous injection of Adalimumab 40mg every two weeks

Timeline

Start date
2018-11-26
Primary completion
2019-10-08
Completion
2020-04-24
First posted
2018-12-28
Last updated
2021-11-17
Results posted
2021-11-17

Locations

1 site across 1 country: Bulgaria

Source: ClinicalTrials.gov record NCT03789292. Inclusion in this directory is not an endorsement.