NCT03788850

Factors Associated With Residual Disease In The Central Cone

Factors Associated With Residual Disease In The Central Cone: A Disease Prediction Model

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 397 (actual)
• Sponsor: National Institute of Cancerología · Other Government
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Cervical conization using the loop electrosurgical excision procedure (LEEP) is the standard treatment for patients with high-grade cervical intraepithelial neoplasia. Several studies have shown that excising a central cone reduces the rate of positive endocervical margins. The purpose of this study is to identify clinicopathological factors associated with residual disease in the central cone and to develop a predictive model to better determine which patients may require this additional procedure.

Detailed description

This study pretends to create a retrospective database including all patient who underwent a loop electrosurgical excision procedure by treatment for high-grade cervical intraepithelial neoplasia and create a a predictive model for top-hat resection in patients with high grade CIN

Conditions

• Cervical Intraepithelial Neoplasia

Timeline

• Start date: 2006-01-01
• Primary completion: 2011-12-31
• Completion: 2016-08-15
• First posted: 2018-12-28
• Last updated: 2020-08-27