NCT03788733

The Efficacy of Melatonin in the Burning Mouth Syndrome

Study of the Efficacy of Melatonin in the Burning Mouth Syndrome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Universidad de Murcia · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Burning mouth ( BMS) syndrome is the oral disorder characterized by an intraoral burning sensation for which no medical or dental cause can be found. The Headache Classification Committee of the International Headache Society (IHS) defines (BMS) as an ''intraoral burning or dysaesthetic sensation, recurring daily for more than 2 hours per day over more than 3 months, without clinically evident causative lesions''. (BMS) is a common, chronic problem that has a negative impact on quality of life. A wide variety of medications have been proposed for treating (BMS) both topical and systemic. Unfortunately, no treatment seems to offer assured results. Melatonin is a naturally occurring hormone secreted by the pineal gland. It has soporific effects with oral administration and is well tolerated. It enhances sleep Melatonin also may help sleep disturbances associated with (BMS) ; however, this remains to be proven.

Detailed description

The purpose of this study is to establish whether melatonin can aid in reducing pain improve sleep quality in (BMS)

Conditions

• Sleep Disorders, Circadian Rhythm

Interventions

Type	Name	Description
DRUG	Melatonin 3 mg	1 time a day for 8 weeks
DRUG	Placebo Oral	1 time a day for 8 weeks

Timeline

• Start date: 2018-12-14
• Primary completion: 2019-06-14
• Completion: 2019-12-14
• First posted: 2018-12-28
• Last updated: 2018-12-28

Locations

1 site across 1 country: Spain