Trials / Unknown
UnknownNCT03787550
PK/PD of the Sedatives, Analgesics and Antibiotics in Patients Receiving ECMO
Pharmacokinetics/Pharmacodynamics of the Sedatives, Analgesics and Antibiotics in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 36 (estimated)
- Sponsor
- Guangdong Provincial People's Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
It is a multi-center, open-label, observational study aimed to understand the pharmacokinetics and pharmacodynamics of the commonly used sedative, analgesic and antibiotic drugs in adult patients supported with extracorporeal membrane oxygenation (ECMO), by measuring the plasma concentrations and the clinical effect of dexmedetomidine, midazolam, butorphanol, remifentanil, sufentanil, propofol, linezolid, tigecycline, teicoplanin, caspofungin, voriconazole and meropenem.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | The Sedatives, analgesics and antibiotics | The sedatives (dexmedetomidine, midazolam, propofol), analgesics (butorphanol, remifentanil, sufentanil), and six antibiotics (linezolid, voriconazole, tigecycline, teicoplanin, caspofungin and meropenem) will be used according to the clinical need. |
Timeline
- Start date
- 2020-02-07
- Primary completion
- 2021-12-31
- Completion
- 2022-03-31
- First posted
- 2018-12-26
- Last updated
- 2020-02-17
Locations
3 sites across 1 country: China
Source: ClinicalTrials.gov record NCT03787550. Inclusion in this directory is not an endorsement.