NCT03787069

Intravenous Lignocaine vs Placebo

Effect of Intravenous Lignocaine vs Placebo on Hemodynamic Response During Intubation

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Indus Hospital and Health Network · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

To assess the mean hemodynamic responses post-intubation in patients given intravenous lignocaine pre-intubation as compared to a placebo pre-intubation in patients undergoing laryngoscopy surgery

Detailed description

After identifying the candidate, details will be carefully discussed with the subject. The subject (or, when necessary, the parent or legal guardian if the subject is younger than 18 years of age or under guardianship) will be read the approved protocol consent form. Patients who have given informed consent to participate in the study will be randomized into one of the two study arms one day before the procedure. The study team present will open the sealed envelopes provided by the Indus Hospital Research Center's Clinical Research Unit (CRU) that provides the study arm allocation. The envelopes will follow the SNOSE protocol.

Conditions

• Hemodynamic Stability Post Intubation in Laryngoscopy Surgery

Interventions

Type	Name	Description
DRUG	iv Lignocaine vs placebo	Lignocaine is available in an ampule of 10 ml containing 20 mg/ml of lignocaine or 2%, Lignocaine will be given in dose of 1.5 mg/kg I/V

Timeline

• Start date: 2017-12-20
• Primary completion: 2018-07-20
• Completion: 2018-07-20
• First posted: 2018-12-26
• Last updated: 2018-12-26

Locations

1 site across 1 country: Pakistan