NCT03786809

Vascular Effect of CIMICIFUGA RACEMOSA

Vascular Effect of CIMICIFUGA RACEMOSA Versus Placebo Evaluated by Flow Mediated Dilatation of Brachial Artery (CRDILA)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Federal University of Minas Gerais · Academic / Other
• Sex: Female
• Age: 45 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Postmenopausal women with vascular symptoms will use Cimifuga Racemosa or Placebo and the effects will be evaluated using Flow-Mediated Dilatation of the brachial artery.

Detailed description

The interruption of the secretion of ovarian steroids after menopause, determines a change in the vascular pattern in several levels. Thus, several vascular effects might interfere with women's health. The use of hormone replacement therapy has contributed to the improvement in these effects. In previous studies, the investigators observed the effects of hormonal replacement therapy in improving such effects in postmenopausal women. The aim of the present study is to evaluate the effects of CIMICIFUGA RACEMOSA on the Flow-Mediated Dilatation of the brachial artery.

Conditions

• Postmenopausal Symptoms

Interventions

Type	Name	Description
DRUG	Cimifuga Racemosa	Experimental group will use 160mg of Cimifuga Racemosa for 28 days
DRUG	Placebo	patients of the placebo group will use placebo once a day for 28 days

Timeline

• Start date: 2016-06-01
• Primary completion: 2019-04-01
• Completion: 2019-05-01
• First posted: 2018-12-26
• Last updated: 2019-08-14

Locations

1 site across 1 country: Brazil