NCT03785990

Fatty Acid Composition of Subcutaneous Adipose Tissue in Infants: A Prospective and Observational Study

Untersuchung Intraoperativ Entnommener Subkutaner Fettgewebeproben Früh- Und Reifgeborener Auf Die Fettsäure-Zusammensetzung Der Triglyceride Und Der Phospholipide Mit Speziellem Fokus Auf Die Mehrfach ungesättigten Fettsäuren Docosahexaensäure Und Arachidonsäure Wissenschaftliche Untersuchung Bei Minderjährigen

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 21 (estimated)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 6 Months
• Healthy volunteers: Not accepted

Summary

The fatty acid composition in blood and subcutaneous adipose tissue of infants that have an clinical indicated operation is studied.

Detailed description

Collection of: * subcutaneous adipose tissue of term infants and preterms after birth and at term during a clinically indicated operation. * blood before the operation. Measurement of the fatty acid composition (especially arachidonic acid and docosahexaenoic acid) in subcutaneous adipose tissue and blood. Aim is to compare the composition of the fatty acids in blood and adipose tissue of preterms at term and term infants. To calculate the fatty acid value in each infant the proportion of adipose tissue is determined with PEAPOD before discharge from hospital.

Conditions

• Prematurity
• Subcutaneous Adipose Tissue

Interventions

Type	Name	Description
OTHER	adipose tissue	taking a sample of the adipose tissue during operation
OTHER	blood	taking a blood sample when a peripheral venous catheter is inserted before operation
DIAGNOSTIC_TEST	PEAPOD	Measurement of the total adipose tissue of the infant with PEAPOD (Air Displacement-Plethysmography, Infant Body Composition System, Cosmed, Rome, Italy)

Timeline

• Start date: 2017-04-03
• Primary completion: 2019-10-31
• Completion: 2019-10-31
• First posted: 2018-12-24
• Last updated: 2018-12-24

Locations

1 site across 1 country: Germany