Trials / Completed
CompletedNCT03784482
Multiple Drug Hypersensitivity Syndrome
Multiple Drug Hypersensitivity Syndrome in a Large Database
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- University Hospital, Montpellier · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Background: Multiple drug hypersensitivity syndrome (MDH) is defined as confirmed drug hypersensitivity reactions (DHRs) to at least 2 chemically and pharmacologically unrelated drugs. Reports of MDH are scarce and poorly specified and studies which diagnose MDH on the basis of positive allergy tests are lacking. Objective: To evaluate retrospectively the frequency and characteristics of MDH patients in a large database. Methods: All the patients who consulted and were tested in our Allergy Unit between September 1996 and February 2018, with confirmed MDH will be included. Clinical history and allergy work-up results will be extracted from our Drug Allergy and Hypersensitivity Database (DAHD). The frequency of MDH will be calculated, MDH patients will be described, the most frequent associations of DHRs will be identified and analysed.
Conditions
Timeline
- Start date
- 2018-12-20
- Primary completion
- 2019-06-30
- Completion
- 2019-07-31
- First posted
- 2018-12-24
- Last updated
- 2019-11-19
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03784482. Inclusion in this directory is not an endorsement.