Clinical Trials Directory

Trials / Completed

CompletedNCT03782467

Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015

A First-in-human, Multicenter, Open-label, Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of Intravenously Administered ATOR-1015

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
33 (actual)
Sponsor
Alligator Bioscience AB · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The aim of the study is to investigate the safety and tolerability of ATOR-1015 when administered as repeated intravenous infusions to patients with advanced and/or refractory solid malignancies.

Conditions

Interventions

TypeNameDescription
BIOLOGICALATOR-1015Bispecific human monoclonal antibody targeting cytotoxic T-lymphocyte associated protein 4 (CTLA-4) and OX40 (also known as CD134)

Timeline

Start date
2019-01-30
Primary completion
2021-03-03
Completion
2021-03-03
First posted
2018-12-20
Last updated
2022-08-18

Locations

5 sites across 2 countries: Denmark, Sweden

Source: ClinicalTrials.gov record NCT03782467. Inclusion in this directory is not an endorsement.

Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015 (NCT03782467) · Clinical Trials Directory