NCT03780868

External DCR Versus Canalicular SI With MMC in NLDO

External Dacryocystorhinostomy Versus Canalicular Silicone Intubation With Mitomycin C in Primary Acquired Nasolacrimal Duct Obstruction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Menoufia University · Academic / Other
• Sex: All
• Age: 21 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

While external DCR is the gold standard procedure for primary NLDO as well as complicated cases, SI with MMC could achieve comparable success rates in primary acquired NLDO, hence should be considered as an alternative as a safe and minimally invasive procedure.

Detailed description

Purpose: To compare external dacryocystorhinostomy versus canalicular silicone intubation with the use of Mitomycin C (MMC) in primary acquired nasolacrimal duct obstruction (NLDO). Methods: the study was carried out at the department of Ophthalmology, Menoufia university Hospital, Egypt, between June 2012 to July 2014. Fifty-six patients who were diagnosed with primary acquired NLDO. Patients were randomly allocated into two groups: thirty cases underwent external DCR and twenty-six cases underwent silicone intubation with MMC.

Conditions

• Primary Acquired Nasolacrimal Duct Obstruction

Interventions

Type	Name	Description
PROCEDURE	external dacryocystorhinostomy	external DCR under general anesthesia with standard sterilization procedures.
PROCEDURE	canalicular silicone intubation with MMC	canalicular silicone intubation with MMC under general anesthesia with standard sterilization procedures.

Timeline

• Start date: 2012-06-01
• Primary completion: 2014-07-01
• Completion: 2014-07-31
• First posted: 2018-12-19
• Last updated: 2018-12-19