NCT03779867

Acute Exercise Intervention in Breast Cancer Survivors

Acute Effects of Exercise on Breast Cancer Biomarkers (ACE) Study

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: Female
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This trial studies how a 45-minute bout of acute exercise in women with a history of breast cancer can affect factors associated with breast cancer and help doctors learn more about how exercise can help prevent breast cancer. In an earlier part of the study, investigators looked at the effects of the same intervention in women without a history of cancer.

Detailed description

OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants undergo a moderate-intensity acute exercise bout over 45 minutes. ARM II: Participants rest by sitting for 45 minutes. EXTENSION: After completion of initial study recruitment and data collection, an extension was approved in 2023. EXTENSION OUTLINE: Participants are randomized to 1 of 2 arms. EXTENSION ARM I: Participants exercise on a stationary bike for 45 minutes. EXTENSION ARM II: Participants rest by sitting for 45 minutes.

Conditions

• Breast Carcinoma

Interventions

Type	Name	Description
BEHAVIORAL	Exercise Intervention	Undergo acute exercise
OTHER	Resting	Seated resting
OTHER	Biomarker Analysis	Correlative studies
OTHER	Questionnaire Administration	Ancillary studies

Timeline

• Start date: 2019-03-25
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2018-12-19
• Last updated: 2025-01-23

Locations

1 site across 1 country: United States