NCT03779516

Effect of Nebulized Lidocaine on Postoperative Sore Throat

Effect of Preoperative Nebulized Lidocaine on Postoperative Sore Throat After Endotracheal Intubation

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Antalya Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the hypothesis that use of preoperative nebulized lidocaine is reduced the incidence of postoperative sore throat after endotracheal intubation.

Detailed description

Adult patients undergoing video-assisted thoracic surgery (VATS) requiring double lumen tube (DLT) endotracheal intubation for one-lung ventilation (OLV) were enrolled in the study. Patients were randomized by means of computer-generated order randomization into two groups: Group C (those who received a saline solution as placebo delivered by nebulization) and Group L (those who received lidocaine delivered by nebulization). At 1, 6 and 24 h after tracheal extubation, an observer blinded to treatments evaluated the patients in terms of sore throat and hoarseness. In addition, Patients' satisfaction, intraoperative and postoperative opioid and analgesics consumption and complaints such as dysphagia, nausea and vomiting were recorded. Hemodynamic variables such as blood pressure and heart rate were also recorded.

Conditions

• Sore Throat

Interventions

Type	Name	Description
OTHER	Saline	Effect of saline on postoperative sore throat
OTHER	Lidocaine	Effect of nebulized lidocaine on postoperative sore throat

Timeline

• Start date: 2018-12-19
• Primary completion: 2019-04-22
• Completion: 2019-07-15
• First posted: 2018-12-19
• Last updated: 2020-04-30

Locations

1 site across 1 country: Turkey (Türkiye)