Trials / Recruiting
RecruitingNCT03779009
Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- Sponsor
- University Hospital, Ghent · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The project investigates the feasibility of laparoscopic fluorescent imaging for the intraoperative detection of the sentinel lymph node (SLN) in colon cancer patients. In addition, the topology of immunological and microenvironmental changes in normal and invaded lymph nodes (LN's) will be correlated to the LN location (anatomical mapping).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | ICG-nanocoll (indocyanine green coupled to the human albumin colloidal particle nanocoll) | Under laparoscopic control, 2.0 ml of ICG-nanocoll will be injected into the subserosa at four quadrants around the tumor. Directly after injection, near infrared (NIR) fluorescence images (Olympus, Tokyo, Japan) will be acquired. SLNs will be identified and marked. |
Timeline
- Start date
- 2018-03-01
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2018-12-19
- Last updated
- 2024-09-19
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT03779009. Inclusion in this directory is not an endorsement.