NCT03776266

The Long-term Clinical Outcomes and Patterns of Transfusion in PCI Patients: Retrospective Cohort Study

The Five-year Pattern of Red Blood Cell Transfusion and Clinical Outcome in Patients Undergoing Percutaneous Coronary Intervention: A Korean Nationwide Longitudinal Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 48,786 (actual)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A nationwide retrospective cohort study. To investigate the long-term patterns of transfusion and clinical outcomes of patients undergoing PCI.

Detailed description

A nationwide retrospective cohort study. Transfusion after PCI may increase a risk, but the long term effects after red blood cell transfusion is known. Longitudinal data is collected from administrative claims in the National Healthcare Insurance Service of Korea. All Korean patient date undergoing PCI inserting stent from January 1, 2011 to December 31, 2011 is extracted. Clinical outcomes until December 31, 2016 is investigated. Primary outcome is the incidence density of red blood cell transfusion. Secondary outcomes are the association of transfusion with major adverse clinical event (MACE) consisting all-cause death, revascularization, critically ill cardiovascular status, or stroke. Incidence density and time-dependent Cox proportional hazard regression is statistically analyzed.

Conditions

• Erythrocyte Transfusion
• Percutaneous Coronary Intervention
• Revascularization

Interventions

Type	Name	Description
PROCEDURE	No intervention is required due to retrospective observational study	Red blood cell transfusion on or after percutaneous coronary intervention

Timeline

• Start date: 2018-10-05
• Primary completion: 2018-11-30
• Completion: 2018-11-30
• First posted: 2018-12-14
• Last updated: 2019-03-28

Locations

1 site across 1 country: South Korea