NCT03775031

Chemical Peels and Fractional Laser on IGF-1 Levels in Skin

Impact of Chemical Peels and Fractional Laser on IGF-1 Levels in Skin

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the impact of fractional laser versus chemical peels on IGF-1 levels in skin.

Detailed description

This study is designed to assess the feasibility of using a fractional non ablative laser and chemical peels to wound skin, and thereby elicit a change in IGF-1. Our hypothesis is that fractional non ablative laser and a TCA chemical peel can induce similar effects as the fractional ablative laser at three months. In other words, our theory is that these approaches can stimulate the production of IGF-1 in older skin and restore UV damage repair and response mechanisms.

Conditions

• Skin Cancer

Interventions

Type	Name	Description
DEVICE	Fractional Laser and Chemical Peel	Fractional 1927 nm Laser, Fractional 1550 nm Laser, and 25% TCA (trichloroacetic acid) peel

Timeline

• Start date: 2019-12-01
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2018-12-13
• Last updated: 2020-10-22

Locations

1 site across 1 country: United States