NCT03772769

Diagnostic Modalities for Severe Odontogenic Infections Using Rapid, Target Enriched Multiplex PCR (TEM- PCR) by Diatherix

Diagnostic Modalities for Severe Odontogenic Infections Using Rapid, Target Enriched Multiplex PCR (TEM- PCR)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to evaluate the sensitivity and specificity of the Target Enriched Multiplex (TEM) polymerase chain reaction (PCR) platform for the rapid molecular diagnosis and treatment of odontogenic deep space neck infections.

Conditions

• Odontogenic Deep Space Neck Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Target Enriched Multiplex PCR (TEM- PCR)	Target Enriched Multiplex PCR (TEM- PCR) assays will be performed and will probe for the typical array of advanced deep space odontogenic infections, as well as MRSA resistance, clindamycin resistance, and the presence of Panton-Valentine leukocidin (PVL) toxin, a toxin produced by some bacteria.
DIAGNOSTIC_TEST	Microbial culture	Standard diagnosis by microbial culture.

Timeline

• Start date: 2019-02-01
• Primary completion: 2020-02-01
• Completion: 2020-02-29
• First posted: 2018-12-11
• Last updated: 2020-03-03

Locations

1 site across 1 country: United States