Clinical Trials Directory

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UnknownNCT03771079

MS Detection of Somatic Mutations in Hematological Malignancies

Evaluation of MassArray Platform Versus Illumina Miseq for the Detection of Driver Mutations in Hematological Malignancies

Status
Unknown
Phase
Study type
Observational
Enrollment
200 (estimated)
Sponsor
University Hospital, Strasbourg, France · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Detection of somatic mutations in hematological malignancies is now routinely assessed by NGS sequencing. This powerful approach is nevertheless time consuming and its costs represent limitation for its availability. An original approach is now available, using mass spectrometry (MS). In this study the analytical performance of both methods will be compared, using samples that were previously analyzed by NGS. The goal of the study is to assess whether MS can represent or not a faster and cheaper way to detect key point mutations in patients suffering from hematological malignancies

Conditions

Timeline

Start date
2018-12-01
Primary completion
2019-12-01
Completion
2019-12-01
First posted
2018-12-10
Last updated
2018-12-26

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT03771079. Inclusion in this directory is not an endorsement.