NCT03770377

Laryngeal Adaptation for Speech and Swallowing

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 21 Years – 100 Years
• Healthy volunteers: Accepted

Summary

This study will test laryngeal adaptation in speech and swallowing function in healthy adults, in patients with cerebral stroke, and in patients with spinocerebellar ataxia type 6. The findings from this proposal will be the first step toward implementing rehabilitation techniques that help patients to prevent speech and swallowing errors before they occur.

Conditions

• Stroke
• Spinocerebellar Ataxia
• Cerebral Stroke
• Dysphagia
• Dysarthria

Interventions

Type	Name	Description
DEVICE	Intermittent Perturbation to Continuous Perturbation	Manipulate the Movement Planning Period (MPP), by interrupting sensory predictions by removing e-stim during the inter-trial interval (Intermittent Perturbation), followed by a washout/de-adaptation period.
DEVICE	Continuous Perturbation to Intermittent Perturbation	Manipulate the Movement Planning Period (MPP), by keep sensory input about the perturbation constant by maintaining e-stim during the inter-trial interval.

Timeline

• Start date: 2018-08-24
• Primary completion: 2019-08-30
• Completion: 2019-08-30
• First posted: 2018-12-10
• Last updated: 2021-06-15

Regulatory

• FDA-regulated device study