NCT03767608

Association Between Irisin, Inflammatory Markers and Metabolic Status in Obese Children With Type 2 Diabetes Mellitus

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Instituto Tecnologico y de Estudios Superiores de Monterey · Academic / Other
• Sex: All
• Age: 6 Years – 17 Years
• Healthy volunteers: —

Summary

The objective of this study was to investigate the association of irisin with inflammatory markers as well with metabolic and anthropometric parameters in children and adolescents with type 2 diabetes mellitus compared with healthy controls.

Detailed description

Mexican children and adolescents previously diagnosed with type 2 diabetes mellitus according to the American Diabetes Association (ADA) criteria were recruited and compared to healthy controls. The participants will undergo: * vital signs measurement (systolic and diastolic blood pressure, heart rate, respiratory rate) * anthropometric variables measurement (BMI, weight, waist circumference, hip circumference, body fat %) * laboratory studies: glucose, triglycerides, HDL-c, C reactive protein, irisin After statistical analyses the investigators will compare the relationship of irisin and the inflammatory profile and the anthropometric parameters of diabetic patients versus lean controls.

Conditions

• Diabetes Mellitus, Type 2
• Pediatric Obesity

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-01-01
• Completion: 2017-01-01
• First posted: 2018-12-06
• Last updated: 2018-12-06

Locations

1 site across 1 country: Mexico