Trials / Completed
CompletedNCT03767114
Estimation of Level of ERAP1 Expression in Lesional and Non Lesional Skin of Psoraitic Patients and Healthy Controls.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 55 (actual)
- Sponsor
- Kasr El Aini Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
A 4mm Punch biopsy is obtained from lesional and non lesional skin of 25 psoraitic patients as well as of 30 controls. Skin biopsy from patients (psoriasis lesional and non lesional) \& control will be kept in lysis solution (which contains RNAase inhibitor) for the stability of the parameter to be assessed. ERAP-1 gene expression will Research Template 5 Final Version: 8/3/2 016 be detected by quantitative real time -PCR, which include RNA extraction, cDNA synthesis \& PCR.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | RT-PCR for ERAP1 detection | Reverse transcriptase -Polymerase Chain Reaction for ERAP1 detection |
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2017-06-01
- Completion
- 2018-12-01
- First posted
- 2018-12-06
- Last updated
- 2018-12-06
Source: ClinicalTrials.gov record NCT03767114. Inclusion in this directory is not an endorsement.