Trials / Unknown
UnknownNCT03766282
Pharmacokinetics in Extracorporeal Membrane Oxygenation
Pharmacokinetics of Antibiotics, Sedative and Analgesic During Extracorporeal Membrane Oxygenation
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- China-Japan Friendship Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The main purpose of the present study is to investigate the risk factors that affect drug pharmacokinetic (PK) during extracorporeal membrane oxygenation (ECMO). To advance understanding of PK variance and improve the patients outcomes during ECMO.
Detailed description
Ex vivo experiments for drug stability testing and ECMO circuits testing in animal models.PK studies in healthy animals and critically ill animal models with or without ECMO to define the PK alterations. Clinical PK studies in critically ill patients on ECMO.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | ECMO | Extracorporeal membrane oxygenation (ECMO) temporarily supports patients with severe cardio-respiratory failure |
Timeline
- Start date
- 2017-09-01
- Primary completion
- 2020-07-01
- Completion
- 2021-12-30
- First posted
- 2018-12-06
- Last updated
- 2018-12-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03766282. Inclusion in this directory is not an endorsement.