NCT03766191

Genetic Predisposition to Food Cue Reactivity in Children

The Relation of Genetic Factors, Food Cues, and Self-Regulation With Excess Consumption and Adiposity in Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 189 (actual)
• Sponsor: Trustees of Dartmouth College · Academic / Other
• Sex: All
• Age: 8 Years – 12 Years
• Healthy volunteers: Accepted

Summary

This study assesses the associations between genetic factors, food-cue-related neural reactivity, self-regulatory capacity, eating in the absence of hunger (EAH), and adiposity gain in children.

Detailed description

The investigators will assess the associations between genetic factors, food-cue-related neural reactivity, eating in the absence of hunger (EAH) in response to food cues, and adiposity gain in children. They will also determine whether self-regulatory capacity modifies these associations. The genetic factors explored specifically include FTO, MC4R, polymorphisms in genes involved in dopaminergic pathways, and a composite genetic risk score built from genome-wide obesity-related loci. \[3/14/2020\]: Study recruitment temporarily halted due to the COVID-19 pandemic

Conditions

• Childhood Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Food Ads	Exposure to foods ads embedded in an age-appropriate TV program
OTHER	Non-food Ads	Exposure to non-food ads embedded in an age-appropriate TV program

Timeline

• Start date: 2019-01-10
• Primary completion: 2024-03-27
• Completion: 2024-03-27
• First posted: 2018-12-06
• Last updated: 2024-11-21

Locations

1 site across 1 country: United States