NCT03766113

Neurofeedback for Upper-limb Recovery After Stroke

Effect of Unimodal (EEG) and Bimodal (EEG-fMRI) Neurofeedback on Upper Limb Recovery After Stroke

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Rennes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Interventional study with minimal risks and constraints, prospective, monocentric.

Detailed description

Neurofeedback (NF) consists on training self-regulation of brain activity by providing real-time information about the participant brain function NF approaches in stroke are usually based on real-time monitoring of brain activity using EEG-NF and involve chronic stroke. Recent studies have revealed the potential of combining EEG and fMRI to achieve a more efficient and specific self-regulation, which may be critical in clinical applications. The aim of this study is to optimize the neurofeedback method coupling EEG and fMRI in healthy subjects then to evaluate the effect of an EEG-NF and a neurofeedback coupling EEG and fMRI versus motor imagery on recovery in the early and chronic stage after stroke.

Conditions

• Stroke

Interventions

Type	Name	Description
OTHER	Neurofeedback coupling electroencephalogram and functional MRI in time actual	One visit : Neurofeedback coupling electroencephalogram and functional MRI in time actual
OTHER	Electroencephalogram-neurofeedback program or Neurofeedback-free mental imaging program with electroencephalogram recording	Interventional group (Electroencephalogram-neurofeedback program) : 24 minutes, 3 times a week for 12 weeks in addition to the traditional rehabilitation program. Controle Group (Neurofeedback-free mental imaging) : 24 minutes, 3 times a week for 12 weeks in addition to the traditional rehabilitation program of reference.
OTHER	Neurofeedback coupling electroencephalogram and functional MRI in time actual or a neurofeedback-free mental imaging program with electroencephalogram recording	Interventional group (5 weeks) : 5 sessions of neurofeedback coupling electroencephalogram and functional MRI in time actual and 9 sessions of electroencephalogram-neurofeedback program Controle Group (5 weeks) : 14 sessions of neurofeedback-free mental imaging program

Timeline

• Start date: 2018-12-20
• Primary completion: 2022-07-28
• Completion: 2022-07-28
• First posted: 2018-12-06
• Last updated: 2022-12-12

Locations

1 site across 1 country: France