NCT03765112

Macular Involvement in Diabetic Retinopathy Evaluated With Swept-Source OCT

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 175 (estimated)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates micro-vascular changes in patients with diabetes. Results of diseased retinas will be compared to healthy controls.

Detailed description

The prevalence of diabetes mellitus (DM) is increasing worldwide. Diabetic retinopathy is the most prevalent complication of DM and a leading cause of visual impairment due to closure of capillaries. High-resolution imaging techniques of the retina and its supplying vascular networks can allow novel insight to subtle changes that cannot be appreciated in standard fundus examination. In this study capillary changes of patients with different severity levels of diabetic retinopathy will be investigated with non-invasive imaging technology to better understand the process of disease progression. Imaging will be done with Optical Coherence tomography (OCT) angiography as well as spectral domain OCT and ultra wide-field imaging.

Conditions

• Diabetes Mellitus
• Diabetic Retinopathy

Interventions

Type	Name	Description
DEVICE	Optical coherence tomography angiography	Multiple scans of the retina will be recorded to evaluate microvascular changes.

Timeline

• Start date: 2018-09-20
• Primary completion: 2022-07-01
• Completion: 2023-03-31
• First posted: 2018-12-05
• Last updated: 2021-10-01

Locations

1 site across 1 country: Canada