NCT03764696

Maternal Oxygen Administration for Fetal Distress II

The Effect of Maternal Long Term High Flow Oxygen Administration During Labor on Umbilical Cord Blood Gases

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: Navy General Hospital, Beijing · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery. However, oxygen delivery depends not just on arterial oxygen content but also on perfusion. Maternal oxygen administration has been used in an attempt to lessen fetal distress by increasing the available oxygen from the mother. However, the effect of supplemental maternal oxygen therapy on fetal acid base status has been debated for more than seven decades. The investigators found the use of 2 L/min maternal oxygen during the second stage of labor did not adversely affect either the umbilical artery pH value or the fetal heart rate (FHR) pattern distribution.

Conditions

• Oxygen Inhalation Therapy
• Labour
• Fetal Distress

Interventions

Type	Name	Description
DEVICE	tight-fitting simple facemask	Oxygen will be administered by facemask at 10 L/min oxygen. The therapy will continue until after delivery

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-10-31
• Completion: 2021-12-31
• First posted: 2018-12-05
• Last updated: 2023-08-15

Locations

3 sites across 1 country: China