NCT03764592

VF Mapping in Brugada and Early Repolarization Syndromes

Mapping of Ventricular Fibrillation (VF) Substrates and VF Arrhythmogenic Sources/Reentrant Circuits in Patients With Brugada and Early Repolarization Syndromes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Pacific Rim Electrophysiology Research Institute · Academic / Other
• Sex: All
• Age: 16 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To determine the values and limitations of ECGI in guiding ablation and risk stratification in patients with BrS and Early Repolarization.

Detailed description

The investigators will study symptomatic BrS and ERs syndrome (N=25) and asymptomatic patients (N=25) age between 16-70 years old to determine values and limitations of non-invasive mapping using electrocardiographic imaging (ECGI) in identifying VF substrates as target sites for catheter ablations in patients with Brugada (BrS) and Early repolarization syndromes (ERS) and also determine the mechanisms of VF in BrS and ERs syndromes.

Conditions

• Brugada Syndrome
• Early Repolarization Syndrome

Interventions

Type	Name	Description
OTHER	radiofrequency ablation	Symptomatic patients whose substrates were identified will undergo catheter ablation; asymptomatic patients will be followed without undergoing catheter ablation.

Timeline

• Start date: 2018-02-23
• Primary completion: 2024-09-01
• Completion: 2024-09-01
• First posted: 2018-12-05
• Last updated: 2024-11-22

Locations

2 sites across 1 country: Thailand