NCT03764228

Human Amniotic Epithelial Cells Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation

Single Arm Clinical Study of Human Amniotic Epithelial Cells in Preventing Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 8 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This is a Single arm clinical study evaluating the safety and efficacy of hAECs in preventing aGVHD after HSCT.

Detailed description

A dose escalation study evaluating the safety and efficacy of human amniotic epithelial cells( hAECs) in preventing acute graft-versus-host(aGVHD) disease after hematopoietic stem cell transplantation(HSCT). The doses were 1×10\^6、2×10\^6、5×\^6 cell/kg, successively.

Conditions

• Acute-graft-versus-host Disease

Interventions

Type	Name	Description
BIOLOGICAL	hAECs	Human amniotic epithelial cells（hAECs）

Timeline

• Start date: 2020-07-01
• Primary completion: 2021-07-01
• Completion: 2022-07-01
• First posted: 2018-12-05
• Last updated: 2020-10-01

Locations

2 sites across 1 country: China