Clinical Trials Directory

Trials / Completed

CompletedNCT03763877

A Study of the Efficacy and Safety of PXL770 Versus Placebo After 12 Weeks of Treatment in Patients With NAFLD

A Randomized, Double-blind, Placebo-controlled, Parallel Group Trial to Assess the Efficacy and Safety of PXL770 Versus Placebo After 12 Weeks of Treatment in Patients With NAFLD

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
121 (actual)
Sponsor
Poxel SA · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study will assess the efficacy and safety of 3 doses of PXL770 versus placebo after 12 weeks of treatment.

Detailed description

The study will be performed in patients with Nonalcoholic Fatty Liver Disease. The primary endpoint will be the assessment of the change in the percentage of liver fat mass (assessed by MRI-PDFF).

Conditions

Interventions

TypeNameDescription
DRUGPXL770Oral capsule
DRUGPlacebo Oral CapsuleOral capsule

Timeline

Start date
2019-03-29
Primary completion
2020-08-03
Completion
2020-08-10
First posted
2018-12-04
Last updated
2021-10-28
Results posted
2021-10-28

Locations

15 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03763877. Inclusion in this directory is not an endorsement.