Clinical Trials Directory

Trials / Completed

CompletedNCT03763240

BSE on Blood Glucose

Effect of BSE on Blood Glucose

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
100 (actual)
Sponsor
Region Skane · Academic / Other
Sex
All
Age
35 Years – 75 Years
Healthy volunteers
Accepted

Summary

Here we will investigate the effect of sulforaphane, provided as a broccoli sprout extract (BSE) on blood glucose in pre-diabetic individuals without metformin treatment. This will address whether BSE could be used to improve glucose control in drug-naïve pre-diabetic individuals. The participants will receive BSE or placebo in a randomized double-blind parallel arm study. The participants will take their study compound once daily over 12 weeks. The primary study variable is fasting glucose.

Detailed description

Here we will investigate the effect of sulforaphane, provided as a broccoli sprout extract (BSE) on blood glucose in pre-diabetic individuals without metformin treatment. This will address whether BSE could be used to improve glucose control in drug-naïve pre-diabetic individuals. The participants will receive BSE or placebo in a randomized double-blind parallel arm study. The participants will take their study compound once daily over 12 weeks. The primary study variable is fasting glucose.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTBSEBSE powder will be provided as dry mixtures in sealed, non-transparent portion size bags. Each BSE bag contains 150 μmole, equal to 0.26 g, sulforaphane at a minimum. The mixtures are suspended with appr. 1 dl water and are ingested once daily in the morning. BSE should be stored at room temperature in dry conditions. The doses of sulforaphane contained in the BSE is not possible to get by eating fresh broccoli, thus it has to be given as an extract.
DIETARY_SUPPLEMENTPlaceboPlacebo powder will be provided as dry mixtures in sealed, non-transparent portion size bags. The mixtures are suspended with appr. 1 dl water and are ingested once daily in the morning.

Timeline

Start date
2018-09-01
Primary completion
2020-12-01
Completion
2020-12-01
First posted
2018-12-04
Last updated
2024-12-16

Locations

1 site across 1 country: Sweden

Source: ClinicalTrials.gov record NCT03763240. Inclusion in this directory is not an endorsement.