NCT03761472

Comparison of Hyaluronic Acid and Platelet-rich Plasma Injections

Comparison of Hyaluronic Acid and Platelet-rich Plasma Injection on Pain, Physical Function and Femoral Cartilage Thickness in Patients With Osteoarthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare the effects of hyaluronic acid injection and platelet rich plasma injection in terms of pain, physical function and femoral cartilage thickness in short term treatment in patients with knee osteoarthritis.

Detailed description

Platelet-rich plasma and hyaluronic acid injections are both popular treatments and commonly used for treatment of knee osteoarthritis. Even though there are many studies investigating the effectiveness of these treatments, the results are mostly qualitative. Also there are a few studies comparing these two treatment modalities. In this study the investigators aim to compare these modalities both for self-reported data (pain, physical function) and objective measurement data (femoral cartilage thickness via ultrasonography). Patients with unilateral osteoarthritis/unilateral complaint will be included in the study. Unaffected side will be controls for each group.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
BIOLOGICAL	Hyaluronic acid injection	Hyaluronic acid 48 mg 2.0% in 2.4 ml solution
BIOLOGICAL	Platelet-rich plasma injection	Platelet-rich plasma injection 5ml

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-01-13
• Completion: 2020-01-13
• First posted: 2018-12-03
• Last updated: 2020-01-18

Locations

1 site across 1 country: Turkey (Türkiye)