Clinical Trials Directory

Trials / Completed

CompletedNCT03760991

Evaluation of the Efficacy and Safety of Insulin Glargine 300 U/mL in Patients With Type 2 Diabetes Mellitus Uncontrolled on Other Kinds of Insulin

A Multicenter, Multinational, Prospective, Interventional, Single-arm, Phase IV Study Evaluating the Clinical Efficacy and Safety of 26 Weeks of Treatment With Insulin Glargine 300 U/mL (Gla-300) in Patients With Type 2 Diabetes Mellitus Uncontrolled on Basal Insulin

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
372 (actual)
Sponsor
Sanofi · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Primary Objective: To assess the efficacy of Gla-300 on glycemic control measured by hemoglobin A1c (HbA1c) change in patients with type 2 diabetes mellitus (T2DM) uncontrolled with their current basal insulin following the switch to Gla-300. Secondary Objectives: To evaluate the effects of Gla-300 on glycemic control, treatment satisfaction, and health care resource utilization (HCRU) outcomes. To evaluate the safety of Gla-300.

Detailed description

Study duration per participant is approximately 29 weeks including a screening period of up to 2 weeks, a 26-week treatment period, and a post treatment follow-up phone call visit at Week 27.

Conditions

Interventions

TypeNameDescription
DRUGINSULIN GLARGINE (U300)Pharmaceutical form: Solution for injection in a prefilled pen Route of administration: Subcutaneous

Timeline

Start date
2018-12-18
Primary completion
2020-09-23
Completion
2020-09-23
First posted
2018-12-03
Last updated
2022-04-25

Locations

14 sites across 14 countries: Argentina, Colombia, Egypt, Hong Kong, India, Indonesia, Lebanon, Malaysia, Peru, Philippines, Saudi Arabia, South Africa, Thailand, Turkey (Türkiye)

Source: ClinicalTrials.gov record NCT03760991. Inclusion in this directory is not an endorsement.