NCT03760133

The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics

The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics: Randomized Controlled, Open-label Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Kosin University Gospel Hospital · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate the relationship between the change of intestinal bacterial flora and the recovery, and the incidence of symptoms such as abdominal discomfort after colonoscopy. And the investigators will also analyze the effects of probiotics on the degree of change, recovery, and symptom development in intestinal flora.

Detailed description

The investigators divided two groups. (total number = 100 subjects) 1. with probiotics group - 50 subjects * Participants included in this group will be taken probiotics for 1 month after bowel preparation for colonoscopy. 2. without probiotics group - 50 subjects * Participants included in this group will not be taken probiotics for 1 month after bowel preparation for colonoscopy.

Conditions

• Gut Microbiota
• Bowel Preparation
• Colonoscopy

Interventions

Type	Name	Description
DRUG	Duolac	Participants included in this group will be taken probiotics for 1 month after bowel preparation for colonoscopy.

Timeline

• Start date: 2018-12-01
• Primary completion: 2019-11-30
• Completion: 2019-12-31
• First posted: 2018-11-30
• Last updated: 2020-02-20

Locations

1 site across 1 country: South Korea