Clinical Trials Directory

Trials / Completed

CompletedNCT03758924

Study of ANAVEX2-73 in Patients With Rett Syndrome

A Double-Blind, Randomized, Placebo-Controlled, Dose Titration Study of ANAVEX2-73 in Patients With Rett Syndrome

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
31 (actual)
Sponsor
Anavex Life Sciences Corp. · Industry
Sex
Female
Age
18 Years – 45 Years
Healthy volunteers
Not accepted

Summary

Phase 2 safety, tolerability and efficacy study is designed as a double-blind, randomized, placebo-controlled study. 7-week placebo-controlled study of ANAVEX2-73 oral solution for the treatment of patients with RTT 18 years or older. A voluntary option will be offered for all patients who meet the exposure criteria for ANAVEX2-73 to continue a 12-week open label extension.

Detailed description

This Phase 2 safety, tolerability and efficacy study is designed as a double-blind, randomized, placebo-controlled study. This is a 7-week placebo-controlled study of ANAVEX2-73 oral solution for the treatment of patients with RTT 18 years or older. A voluntary option will be offered for all patients who meet the exposure criteria for ANAVEX2-73 to continue a 12-week open label extension.

Conditions

Interventions

TypeNameDescription
DRUGANAVEX2-73Liquid oral solution
DRUGPlaceboLiquid oral solution

Timeline

Start date
2019-02-28
Primary completion
2020-10-30
Completion
2020-10-30
First posted
2018-11-29
Last updated
2021-01-12

Locations

8 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03758924. Inclusion in this directory is not an endorsement.