Clinical Trials Directory

Trials / Completed

CompletedNCT03758404

Gene Therapy for Achromatopsia (CNGA3)

An Open Label, Multi-centre, Phase I/II Dose Escalation Trial of a Recombinant Adeno-associated Virus Vector (AAV2/8-hG1.7p.coCNGA3) for Gene Therapy of Children and Adults With Achromatopsia Owing to Defects in CNGA3

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
11 (actual)
Sponsor
MeiraGTx UK II Ltd · Industry
Sex
All
Age
3 Years
Healthy volunteers
Not accepted

Summary

A clinical trial of adeno-associated virus vector (AAV) CNGA3 retinal gene therapy for patients with achromatopsia

Detailed description

CNGA3 retinal gene therapy for patients with achromatopsia

Conditions

Interventions

TypeNameDescription
BIOLOGICALadeno-associated virus vector AAV- CNGA3Adeno-associated virus (AAV) gene therapy for defects in CNGA3 gene

Timeline

Start date
2019-08-12
Primary completion
2021-06-10
Completion
2021-06-10
First posted
2018-11-29
Last updated
2022-12-01
Results posted
2022-02-11

Locations

2 sites across 2 countries: United States, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03758404. Inclusion in this directory is not an endorsement.

Gene Therapy for Achromatopsia (CNGA3) (NCT03758404) · Clinical Trials Directory