NCT03756272

Stellate Ganglion Block to Reduce Hot Flushes

Short-term Efficacy of Stellate Ganglion Block to Reduce Hot Flushes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Rijnstate Hospital · Academic / Other
• Sex: Female
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure

Detailed description

Hot flushes are the most common symptom of menopause for which postmenopausal (PMP) women seek medical help, in 20% of PMP women hot flushes can persist for up to 15 years. A possible treatment for hot flushes is stellate ganglion block (SGB), used as a means to interrupt parts of the sympathetic nervous system involved in temperature regulation. Single centre randomized double blind placebo controlled intervention study Study period of 6 months in which patients will fill out on set time points 5 questionnaires regarding quality of life and keep a diary on hot flush frequency and severity during1 week on the same time points. Study population: Postmenopausal women aged 30-70 years old with no other causes of flushing present. Intervention (if applicable) Intervention: Stellate ganglion block versus sham procedure Follow up with questionnaires during 6 months.

Conditions

• Hot Flash
• Stellate Ganglion Block
• Postmenopausal
• Hot Flushes

Interventions

Type	Name	Description
PROCEDURE	Bupivacaine block	stellate ganglion bupivacaine injection
PROCEDURE	Placebo ganglion block	stellate ganglion sodium chloride injection

Timeline

• Start date: 2017-09-01
• Primary completion: 2018-04-28
• Completion: 2019-02-01
• First posted: 2018-11-28
• Last updated: 2020-03-11

Locations

1 site across 1 country: Netherlands