NCT03755752

Safety of Trypan Blue on Endothelium of Diabetic Retinopathy Patients

Safety of Trypan Blue Capsule Staining to Corneal Endothelium in Patients With Diabetic Retinopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 25 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study examines the use of Trypan Blue staining of the corneal endothelium in patients undergoing phacoemulsification. It is a single-center prospective, randomized individual cohort study. One eye in each patient with diabetic retinopathy will undergo phacoemulsification without Trypan Blue capsule staining (control eye) while the other eye will undergo phacoemulsification with Trypan Blue capsule staining (study eye). Both eyes will undergo intraocular lens implantation. Preoperative and four-week postoperative quantitative and qualitative morphometric endothelial cell analyses of the cornea will be performed using noncontact specular microscopy.

Conditions

• Cataract Diabetic

Interventions

Type	Name	Description
PROCEDURE	Phacoemulsification with and without Trypan Blue capsule staining	Phacoemulsification for patients with diabetic retinopathy having cataract in both eyes. One eye underwent phacoemulsification with trypan blue capsule staining and the other eye underwent phacoemulsification without trypan blue.

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-07-25
• Completion: 2018-08-31
• First posted: 2018-11-28
• Last updated: 2018-11-28

Locations

1 site across 1 country: Egypt