NCT03753607

Renal Venous Flow and Cardiac Surgery-associated Acute Kidney Injury

Changes in Doppler-derived Renal Venous Flow and Adverse Renal Outcomes Following Cardiac Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: University of Giessen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The prospective single-center study investigates the association between changes in Doppler-derived renal venous flow and cardiac surgery-associated acute kidney injury (CSA-AKI).

Detailed description

CSA-AKI is a common postoperative complication in patients undergoing open heart surgery, and is associated with increased mortality and morbidity. Venous congestion has been identified as the principal cause of cardiorenal decompensation in patients with heart failure but the relative contribution of congestion-driven renal function decline in CSA-AKI is not well studied. The prospective single-center study investigates whether serial Doppler-derived renal venous flow assessments could help identify subset of patients with cardiorenal syndrome and subclinical renal congestion at high risk of CSA-AKI.

Conditions

• Acute Kidney Injury
• Cardiorenal Syndrome

Interventions

Type	Name	Description
OTHER	No intervention	No intervention

Timeline

• Start date: 2018-12-20
• Primary completion: 2022-01-14
• Completion: 2023-11-24
• First posted: 2018-11-27
• Last updated: 2023-12-01

Locations

1 site across 1 country: Germany