NCT03748524

Analysis of Antigen Specific B Cell Responses to Immunization With Influenza Virus Vaccine

Washington University (WU) 321: Analysis of Antigen Specific B Cell Responses to Immunization With Influenza Virus Vaccine: Fine Needle Aspiration (FNA) and Bone Marrow Aspiration (BMA)

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Immunization with the inactivated influenza vaccine with blood samples collected at 7 visits (baseline, day 7, 14, 28, 60, 90 and 180, fine needle aspiration (FNAs) from axillary lymph nodes at baseline, days, 4, 14, 28, 60 and 180. BMA at baseline, days 28 and 180.

Detailed description

IM Immunization with the inactivated influenza vaccine with blood samples collected at 7 visits (baseline, day 7, 14, 28, 60, 90 and 180, fine needle aspiration (FNAs) from axillary lymph nodes at baseline, days, 4, 14, 28, 60 and 180. BMA at baseline, days 28 and 180.

Conditions

• Immunity, Cellular

Interventions

Type	Name	Description
DRUG	Influenza Vaccine	Influenza Vaccine,Quadrivalent SIngle vaccination all participants at day 0

Timeline

• Start date: 2018-10-29
• Primary completion: 2021-09-30
• Completion: 2022-06-20
• First posted: 2018-11-21
• Last updated: 2025-01-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study