Trials / Recruiting
RecruitingNCT03744819
Biomarkers for Prediction of Tumor Response to Radiotherapy
Exploration of Potential Biomarkers to Predict Tumor Response to Radiotherapy in Patients With Solid Tumors
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Chuangzhen Chen · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study aims to explore potential biomarkers for prediction of therapeutic outcomes in patients with solid tumors after radiotherapy
Detailed description
Patients pathologically confirmed with solid tumors that requires radiotherapy or surgery will be recruited to this study. Tumor samples were obtained from patients underwent surgery to establish the baseline status of biomarker assessed. Peripheral and microbiota will also be collected before and after surgery. For patients undergoing radiotherapy, tumor biopsy as well as collection of blood samples and microbiota will be performed during the course of treatment. These biological specimens will be used for assessment of tumor phenotypes and for exploration of potential biomarkers that could predict the tumor response to therapeutics and prognsis in patients with solid tumors.
Conditions
Timeline
- Start date
- 2018-10-29
- Primary completion
- 2025-11-30
- Completion
- 2026-11-30
- First posted
- 2018-11-16
- Last updated
- 2024-02-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03744819. Inclusion in this directory is not an endorsement.