Trials / Unknown
UnknownNCT03742869
HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
A Multi-omics Study on the Human Papillomavirus Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Lei Li · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study aims to analyze the multi-omics results between uterine cervical adenocarcinoma patients with and without human papillomavirus (HPV) infections. The multi-omics profiles include genome wide association study (GWAS), whole exome sequencing, analysis of transcriptomics and metabolomics. The HPV integration status is interpreted by GWAS. A comprehensive multi-omics will reveal the role of HPV integration in the molecular mechanism of tumorigenesis and prognosis of uterine cervical adenocarcinoma.
Conditions
- Cervical Adenocarcinoma
- Human Papillomavirus
- Genome-wide Association Study
- Whole Exome Sequencing
- Transcriptome
- Metabolome
- Tumorigenesis
- Prognosis
Interventions
| Type | Name | Description |
|---|---|---|
| COMBINATION_PRODUCT | A multi-omics analysis | A multi-omics analysis including genome-wide association study, whole exome sequencing, transcriptomics and metabolomics. |
Timeline
- Start date
- 2018-11-10
- Primary completion
- 2021-11-23
- Completion
- 2021-11-23
- First posted
- 2018-11-15
- Last updated
- 2018-11-15
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03742869. Inclusion in this directory is not an endorsement.