NCT03741309

Comparison of Clinical Efficacy of a Dentifrice Containing 5% Fluoro Calcium Phosphosilicate to a Dentifrice Containing Calcium Sodium Phosphosilicate on Dentinal Hypersensitivity

Comparison of Clinical Efficacy of a Dentifrice Containing 5% Fluoro Calcium Phosphosilicate to a Dentifrice Containing Calcium Sodium Phosphosilicate and to a Placebo on Dentinal Hypersensitivity : a Randomized Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 131 (actual)
• Sponsor: Government Dental College and Research Institute, Bangalore · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing calcium sodium phosphosilicate on Dentinal Hypersensitivity (DH) compared to a placebo over a period of 6 weeks.

Detailed description

A total of 131 subjects were divided into 3 groups randomly. Group I was given the dentifrice containing 5% fluoro calcium phosphosilicate ,Group II was given the dentifrice containing calcium sodium phosphosilicate and group III was given placebo. Sensitivity scores (VAS score) were recorded at baseline, 2 weeks, 6 weeks.

Conditions

• Dentinal Hypersensitivity

Interventions

Type	Name	Description
OTHER	5% fluorocalcium phosphosilicate dentifrice	dentifrice containing 5% fluorocalcium phosphosilicate and VAS score assessed at Baseline, 2 weeks, 6 weeks.
OTHER	Calcium sodium phosphosilicate	Calcium sodium phosphosilicatand VAS score assessed at Baseline, 2weeks, 6 weeks.
OTHER	Placebo dentrifice	placebo dentifrice and VAS score assessed at Baseline, 2weeks, 6 weeks.

Timeline

• Start date: 2017-12-20
• Primary completion: 2018-02-16
• Completion: 2018-02-24
• First posted: 2018-11-14
• Last updated: 2018-11-14

Locations

1 site across 1 country: India